The demographic history and mutational load of African hunter-gatherers and farmers

african-admixture-rainforest

Interesting new article (behind paywall), The demographic history and mutational load of African hunter-gatherers and farmers, Nat Ecol Evol (2018)

Abstract (emphasis mine):

Understanding how deleterious genetic variation is distributed across human populations is of key importance in evolutionary biology and medical genetics. However, the impact of population size changes and gene flow on the corresponding mutational load remains a controversial topic. Here, we report high-coverage exomes from 300 rainforest hunter-gatherers and farmers of central Africa, whose distinct subsistence strategies are expected to have impacted their demographic pasts. Detailed demographic inference indicates that hunter-gatherers and farmers recently experienced population

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