Tag: pca

Two more studies on the genetic history of East Asia: Han Chinese and Thailand

chinese-eurasian-drift

A comprehensive map of genetic variation in the world’s largest ethnic group – Han Chinese, by Charleston et al. (2017).

It is believed – based on uniparental markers from modern and ancient DNA samples and array-based genome-wide data – that Han Chinese originated in the Central Plain region of China during prehistoric times, expanding with agriculture and technology northward and southward, to become the largest Chinese ethnic group.

Abstract:

As are most non-European populations around the globe, the Han Chinese are relatively understudied in population and medical genetics studies. From low-coverage whole-genome sequencing of 11,670 Han Chinese women we

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Effective migration in Western Eurasia reveals fine-scale migration surface features

map-effective-migration-eurasia

Interesting poster from SMBE 2017, Maps of effective migration as a summary of global human genetic diversity, by Benjamin Peter, Desislava Petkova, Matthew Stephens & John Novembre, of the JNPopGen group of the University of Chicago.

You can read the full poster in the original PDF, or in compressed image. The following are important excerpts:

Aim: To answer the following questions:

  • Which regions have high/low effective migration?
  • How well is human genetic diversity explained by this pure isolation-by-distance model?
  • How does the explanatory performance of EEMS compare to PCA?

Method: It uses the

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